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FANCA (phospho Ser1149) rabbit pAb
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ES5193
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: FANCA (phospho Ser1149) rabbit pAb
反应性: Human;Rat;Mouse;
别名: FANCA; FAA; FACA; FANCH; Fanconi anemia group A protein; Protein FACA
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human FANCA around the phosphorylation site of Ser1149. AA range:1121-1170
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 162kD
基因ID: 2175
蛋白序列: O15360
细胞定位: Nucleus. Cytoplasm. The major form is nuclear. The minor form is cytoplasmic.
研究背景: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq, Jul
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