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APOBEC3A rabbit pAb
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ES5099
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: APOBEC3A rabbit pAb
反应性: Human;Rat;Mouse;
别名: APOBEC3A; Probable DNA dC->dU-editing enzyme APOBEC-3A; Phorbolin-1
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human APOBEC3A. AA range:27-76
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 26kD
基因ID: 200315
蛋白序列: P31941
细胞定位: Nucleus. Cytoplasm.
研究背景: This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided b
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