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DOCK 180 rabbit pAb
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ES5015
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: DOCK 180 rabbit pAb
反应性: Human;Mouse
别名: DOCK1; Dedicator of cytokinesis protein 1; 180 kDa protein downstream of CRK; DOCK180
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human DOCK1. AA range:1661-1710
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 215kD
基因ID: 1793
蛋白序列: Q14185
细胞定位: Cytoplasm . Membrane . Recruited to membranes via its interaction with phosphatidylinositol 3,4,5-trisphosphate. .
研究背景: This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],
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