KV8.2 rabbit pAb-ELK科鹿生物-ELISA试剂盒、抗体、蛋白、分子

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KV8.2 rabbit pAb

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ES4995

规格：	价格：
50µL	￥1280.00
100µL	￥1980.00

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Overview

产品名称:	KV8.2 rabbit pAb
反应性:	Human;Mouse
别名:	KCNV2; Potassium voltage-gated channel subfamily V member 2; Voltage-gated potassium channel subunit Kv8.2
宿主:	Rabbit
稀释比:	WB 1:500-2000;IHC-p 1:50-300
免疫原:	The antiserum was produced against synthesized peptide derived from human KCNV2. AA range:187-236
储存条件:	-20°C/1 year
克隆性:	Polyclonal
抗体亚型:	IgG
浓度:	1 mg/ml
实测条带:	62kD
基因ID:	169522
蛋白序列:	Q8TDN2
细胞定位:	Cell membrane; Multi-pass membrane protein. Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1.
研究背景:	Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues. [provided by RefSeq, Jul 2008],

Western Blot analysis of MCF-7 cells using KV8.2 Polyclonal Antibody
Western blot analysis of lysates from MCF-7 cells, using KCNV2 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

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