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ZnT-8 rabbit pAb
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ES4993
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: ZnT-8 rabbit pAb
反应性: Human;Rat;Mouse;
别名: SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human SLC30A8. AA range:171-220
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 41kD
基因ID: 169026
蛋白序列: Q8IWU4
细胞定位: Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, secretory vesicle membrane ; Multi-pass membrane protein . Associated with insulin and glucagon secretory granules. .
研究背景: The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010],
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