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Claudin-7 (phospho Tyr210) rabbit pAb
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ES4792
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Claudin-7 (phospho Tyr210) rabbit pAb
反应性: Human;Mouse;Rat
别名: CLDN7; CEPTRL2; CPETRL2; Claudin-7; CLDN-7
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human Claudin 7 around the phosphorylation site of Tyr210. AA range:162-211
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 32kD
基因ID: 1366
蛋白序列: O95471
细胞定位: Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane . Cell junction, tight junction . Co-localizes with EPCAM at the basolateral cell membrane and tight junction. .
研究背景: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010],
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