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COX10 rabbit pAb
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ES4780
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: COX10 rabbit pAb
反应性: Human;Rat;Mouse;
别名: COX10; Protoheme IX farnesyltransferase; mitochondrial; Heme O synthase
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human COX10. AA range:98-147
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 49kD
基因ID: 1352
蛋白序列: Q12887
细胞定位: Mitochondrion membrane; Multi-pass membrane protein.
研究背景: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lys
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