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Adenosine A2A-R rabbit pAb
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ES4777
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Adenosine A2A-R rabbit pAb
反应性: Human;Rat;Mouse;
别名: ADORA2A; ADORA2; Adenosine receptor A2a
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human ADORA2A. AA range:120-169
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 37kD
基因ID: 135
蛋白序列: P29274
细胞定位: Cell membrane ; Multi-pass membrane protein . Colocalizes with GAS2L2 at neuronal processes. .
研究背景: adenosine A2a receptor(ADORA2A) Homo sapiens This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript compos
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