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COL7A1 rabbit pAb
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ES4749
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: COL7A1 rabbit pAb
反应性: Human;Mouse
别名: COL7A1; Collagen alpha-1(VII) chain; Long-chain collagen; LC collagen
宿主: Rabbit
稀释比: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human Collagen VII alpha1. AA range:1841-1890
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 295kD
基因ID: 1294
蛋白序列: Q02388
细胞定位: Secreted, extracellular space, extracellular matrix, basement membrane.
研究背景: collagen type VII alpha 1 chain(COL7A1) Homo sapiens This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008],
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