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MKP-5 rabbit pAb
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ES4621
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: MKP-5 rabbit pAb
反应性: Human;Mouse;Rat
别名: DUSP10; MKP5; Dual specificity protein phosphatase 10; Mitogen-activated protein kinase phosphatase 5; MAP kinase phosphatase 5; MKP-5
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
免疫原: Synthesized peptide derived from MKP-5 . at AA range: 330-410
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 52kD
基因ID: 11221
蛋白序列: Q9Y6W6
细胞定位: Cytoplasm. Nucleus.
研究背景: dual specificity phosphatase 10(DUSP10) Homo sapiens Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],
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