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Calpain 10 rabbit pAb
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ES4603
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Calpain 10 rabbit pAb
反应性: Human;Rat;Mouse;
别名: CAPN10; KIAA1845; Calpain-10; Calcium-activated neutral proteinase 10; CANP 10
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
免疫原: Synthesized peptide derived from the N-terminal region of human Calpain 10.
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 75kD
基因ID: 11132
蛋白序列: Q9HC96
细胞定位: intracellular,cell,mitochondrion,cytosol,plasma membrane,
研究背景: Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq,
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