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C/EBP α (phospho Thr226) rabbit pAb
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ES4487
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: C/EBP α (phospho Thr226) rabbit pAb
反应性: Human;Mouse;Rat;Monkey
别名: CEBPA; CCAAT/enhancer-binding protein alpha; C/EBP alpha
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human C/EBP-alpha around the phosphorylation site of Thr226. AA range:192-241
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 42,also have 30kd isform
基因ID: 1050
蛋白序列: P49715
细胞定位: Nucleus .; [Isoform 4]: Nucleus, nucleolus .
研究背景: This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013],
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