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Vav3 rabbit pAb
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ES4476
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Vav3 rabbit pAb
反应性: Human;Mouse
别名: VAV3; Guanine nucleotide exchange factor VAV3; VAV-3
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human VAV3. AA range:139-188
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 98kD
基因ID: 10451
蛋白序列: Q9UKW4
细胞定位: intracellular,cytosol,plasma membrane,extracellular exosome,
研究背景: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
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