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R-cadherin rabbit pAb
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ES4408
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: R-cadherin rabbit pAb
反应性: Human;Mouse
别名: CDH4; Cadherin-4; Retinal cadherin; R-CAD; R-cadherin
宿主: Rabbit
稀释比: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human CDH4. AA range:731-780
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 100kD
基因ID: 1002
蛋白序列: P55283
细胞定位: Cell membrane; Single-pass type I membrane protein.
研究背景: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
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