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GDF-6 rabbit pAb
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ES4378
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: GDF-6 rabbit pAb
反应性: Human;Mouse;Rat
别名: GDF6; GDF16; Growth/differentiation factor 6; GDF-6; Growth/differentiation factor 16
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from the Internal region of human GDF6. AA range:311-360
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 50kD
基因ID: 392255
蛋白序列: Q6KF10
细胞定位: Secreted .
研究背景: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016],
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