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CD305 rabbit pAb
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ES4364
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: CD305 rabbit pAb
反应性: Human;Rat;Mouse;
别名: LAIR1; CD305; Leukocyte-associated immunoglobulin-like receptor 1; LAIR-1; hLAIR1; CD305
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from the Internal region of human LAIR1. AA range:21-70
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 32kD
基因ID: 3903
蛋白序列: Q6GTX8
细胞定位: Cell membrane ; Single-pass type I membrane protein .
研究背景: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
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