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PPP1R15B rabbit pAb
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ES4301
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: PPP1R15B rabbit pAb
反应性: Human;Rat;Mouse;
别名: PPP1R15B; Protein phosphatase 1 regulatory subunit 15B
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from the Internal region of human PPP1R15B. AA range:411-460
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 78kD
基因ID: 84919
蛋白序列: Q5SWA1
细胞定位: protein phosphatase type 1 complex,
研究背景: This gene encodes a protein phosphatase I-interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular stress. The transcribed messenger RNA contains two upstream open reading frames (ORFs) that repress translation of the main protein coding ORF under normal conditions, while the protein coding ORF is expressed at high levels in response to stress. Continual translation of the mRNA under conditions of eukaryotic translation initiation factor 2A inactivation is thought to create a feedback loop for reactivation of the gene during recovery from stress. In addition, it has been shown that this protein plays a role in membrane traffic that is independent of translation and that it is required for exocytosis from erythroleukemia cells. Allelic variants of this gene are associated with mi
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