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CD85c rabbit pAb
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ES4240
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

Product name: CD85c rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: LILRB5; LIR8; Leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; LIR-8; CD85c
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human LILRB5. AA range:21-70
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 65kD
GeneID: 10990
Human Swiss-Prot No: O75023
Cellular localization: Membrane; Single-pass type I membrane protein.
Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
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