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NCoA-3 rabbit pAb
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ES4237
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: NCoA-3 rabbit pAb
反应性: Human;Mouse;Rat
别名: NCOA3; AIB1; BHLHE42; RAC3; TRAM1; Nuclear receptor coactivator 3; NCoA-3; ACTR; Amplified in breast cancer 1 protein; AIB-1; CBP-interacting protein; pCIP; Class E basic helix-loop-helix protein 42; bHLHe42; Receptor-associated coactivator 3; RAC-3; Steroid receptor coactivator protein 3; SRC-3; Thyroid hormone receptor activator molecule 1; TRAM-1
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
免疫原: Synthesized peptide derived from the Internal region of human NCoA-3.
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 160kD
基因ID: 8202
蛋白序列: Q9Y6Q9
细胞定位: Cytoplasm. Nucleus. Mainly cytoplasmic and weakly nuclear. Upon TNF activation and subsequent phosphorylation, it translocates from the cytoplasm to the nucleus.
研究背景: The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010],
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