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FOXP3 rabbit pAb
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ES4176
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: FOXP3 rabbit pAb
反应性: Human;Mouse;Rat;Pig
别名: FOXP3; IPEX; JM2; Forkhead box protein P3; Scurfin
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from the C-terminal region of human FOXP3. AA range:381-430
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 47kD
基因ID: 50943
蛋白序列: Q9BZS1
细胞定位: Nucleus . Cytoplasm . Predominantly expressed in the cytoplasm in activated conventional T-cells whereas predominantly expressed in the nucleus in regulatory T-cells (Treg). The 41 kDa form derived by proteolytic processing is found exclusively in the chromatin fraction of activated Treg cells (By similarity). .
研究背景: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
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