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ApoA-I rabbit pAb
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ES4169
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview 文献(1)

产品名称: ApoA-I rabbit pAb
反应性: Human;Mouse
别名: APOA1; Apolipoprotein A-I; Apo-AI; ApoA-I; Apolipoprotein A1
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from the Internal region of human APOA1. AA range:81-130
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 31kD
基因ID: 335
蛋白序列: P02647
细胞定位: Secreted.
研究背景: This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015],
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