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GDF-5 rabbit pAb
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ES4032
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: GDF-5 rabbit pAb
反应性: Human;Mouse;Rat
别名: GDF5; CDMP1; Growth/differentiation factor 5; GDF-5; Cartilage-derived morphogenetic protein 1; CDMP-1; Radotermin
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from the Internal region of human GDF5. AA range:361-410
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 55kD
基因ID: 8200
蛋白序列: P43026
细胞定位: Secreted . Cell membrane .
研究背景: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis. [provided by RefSeq, Aug 2016],
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