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CD207 rabbit pAb
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ES4005
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: CD207 rabbit pAb
反应性: Human;Rat;Mouse;
别名: CD207; CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from the Internal region of human CD207. AA range:61-110
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 38kD
基因ID: 50489
蛋白序列: Q9UJ71
细胞定位: Membrane ; Single-pass type II membrane protein . Found in Birbeck granules (BGs), which are organelles consisting of superimposed and zippered membranes.
研究背景: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010],
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