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CD158z rabbit pAb
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ES4003
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

Product name: CD158z rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: KIR3DL3; CD158Z; KIR3DL7; KIRC1; Killer cell immunoglobulin-like receptor 3DL3; CD158 antigen-like family member Z; Killer cell inhibitory receptor 1; CD158z
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human KIR3DL3. AA range:231-280
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 45kD
GeneID: 100133046
Human Swiss-Prot No: Q8N743
Cellular localization: Cell membrane; Single-pass type I membrane protein.
Background: killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3(KIR3DL3) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the
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