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Glypican-3 rabbit pAb
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ES3936
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

Product name: Glypican-3 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: GPC3; OCI5; Glypican-3; GTR2-2; Intestinal protein OCI-5; MXR7
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GPC3. AA range:461-510
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 70kD
GeneID: 2719
Human Swiss-Prot No: P51654
Cellular localization: Cell membrane ; Lipid-anchor, GPI-anchor ; Extracellular side .
Background: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009],
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