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TF rabbit pAb
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ES3924
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: TF rabbit pAb
反应性: Human;Rat;Mouse;
别名: F3; Tissue factor; TF; Coagulation factor III; Thromboplastin; CD142
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from the Internal region of human F3. AA range:131-180
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 33kD
基因ID: 2152
蛋白序列: P13726
细胞定位: [Isoform 1]: Membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .
研究背景: This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
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