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BNIP-3 rabbit pAb
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ES3884
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: BNIP-3 rabbit pAb
反应性: Human;Rat;Mouse;
别名: BNIP3; NIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from the Internal region of human BNIP3. AA range:71-120
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 22kD
基因ID: 664
蛋白序列: Q12983
细胞定位: Mitochondrion. Mitochondrion outer membrane; Single-pass membrane protein. Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the mitochondria. Colocalizes with SPATA18 at the mitochondrion outer membrane.
研究背景: This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014],
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