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IL-10 rabbit pAb
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ES3868
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview 文献(1)

产品名称: IL-10 rabbit pAb
反应性: Human;Mouse;Rat
别名: IL10; Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from the Internal region of human IL10. AA range:71-120
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 20kD
基因ID: 3586
蛋白序列: P22301
细胞定位: Secreted.
研究背景: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011],
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