POLM; polmu; DNA-directed DNA/RNA polymerase mu; Pol Mu; Terminal transferase
Source:
Rabbit
Dilutions:
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:
Synthesized peptide derived from DNA Pol μ . at AA range: 210-290
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
54kD
GeneID:
27434
Human Swiss-Prot No:
Q9NP87
Cellular localization:
Nucleus .
Background:
catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,