Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:
Synthesized peptide derived from the Internal region of human IL-31Rα.
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
82kD
GeneID:
133396
Human Swiss-Prot No:
Q8NI17
Cellular localization:
Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, presynaptic cell membrane . Cell projection, axon .
Background:
The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011],