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Stathmin-2 rabbit pAb
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ES3806
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Stathmin-2 rabbit pAb
反应性: Human;Mouse;Rat
别名: STMN2; SCG10; SCGN10; Stathmin-2; Superior cervical ganglion-10 protein; Protein SCG10
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/5000. Not yet tested in other applications.
免疫原: Synthesized peptide derived from the Internal region of human Stathmin-2.
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 20kD
基因ID: 11075
蛋白序列: Q93045
细胞定位: Cytoplasm . Cytoplasm, perinuclear region . Cell projection, growth cone. Membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, axon. Golgi apparatus. Endosome . Cell projection, lamellipodium. Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity). Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia. .
研究背景: This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010],
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