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Gl Syn rabbit pAb
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ES3765
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Gl Syn rabbit pAb
反应性: Human;Mouse;Rat
别名: GLUL; GLNS; Glutamine synthetase; GS; Glutamate decarboxylase; Glutamate--ammonia ligase
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human Gl Syn. AA range:295-344
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 42kD
基因ID: 2752
蛋白序列: P15104
细胞定位: Cytoplasm, cytosol . Microsome . Mitochondrion . Cell membrane ; Lipid-anchor . Mainly localizes in the cytosol, with a fraction associated with the cell membrane. .
研究背景: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
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