ACADM; Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; MCAD
宿主:
Rabbit
稀释比:
WB 1:500-2000;IHC-p 1:50-300
免疫原:
The antiserum was produced against synthesized peptide derived from human MCAD. AA range:134-183
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
46kD
基因ID:
34
蛋白序列:
P11310
细胞定位:
Mitochondrion matrix .
研究背景:
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],