ACADM; Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; MCAD
Source:
Rabbit
Dilutions:
WB 1:500-2000;IHC-p 1:50-300
Immunogen:
The antiserum was produced against synthesized peptide derived from human MCAD. AA range:134-183
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
46kD
GeneID:
34
Human Swiss-Prot No:
P11310
Cellular localization:
Mitochondrion matrix .
Background:
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],