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UBE3C rabbit pAb
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ES3667
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: UBE3C rabbit pAb
反应性: Human;Rat;Mouse;
别名: UBE3C; KIAA0010; KIAA10; Ubiquitin-protein ligase E3C; HectH2
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: Synthesized peptide derived from the Internal region of human UBE3C.
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 125kD
基因ID: 148581
蛋白序列: Q15386
细胞定位: proteasome complex,intracellular,nucleus,cytoplasm,
研究背景: function:E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.,miscellaneous:A cysteine residue is required for ubiquitin-thioester formation.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 1 IQ domain.,subunit:Interacts with 26S proteasomes. Binds CAND2.,tissue specificity:Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas.,
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