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TLK1 rabbit pAb
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ES3616
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

Product name: TLK1 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: TLK1; KIAA0137; Serine/threonine-protein kinase tousled-like 1; PKU-beta; Tousled-like kinase 1
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human TLK1. AA range:201-250
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 87kD
GeneID: 9874
Human Swiss-Prot No: Q9UKI8
Cellular localization: Nucleus .
Background: Serine/threonine-protein kinase tousled-like 1 encoded by TLK1 is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.
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