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TLE4 rabbit pAb
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ES3615
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

Product name: TLE4 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: TLE4; KIAA1261; Transducin-like enhancer protein 4
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human TLE4. AA range:161-210
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 83kD
GeneID: 7091
Human Swiss-Prot No: Q04727
Cellular localization: Nucleus.
Background: caution:Product of a dubious CDS prediction. Found in the 3'UTR of TLE4. No homolog. Large scale identification of a phosphorylated peptide (PubMed:15302935) would require further confirmation.,function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.,similarity:Belongs to the WD repeat Groucho/TLE family.,similarity:Contains 7 WD repeats.,subunit:Homooligomer and heterooligomer with other family members. Binds PAX5, LEF1, TCF7, TCF7L1 and TCF7L2.,tissue specificity:In all tissues examined, mostly in brain, and muscle.,
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