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SOD-1 rabbit pAb
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ES3478
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

Product name: SOD-1 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human SOD-1. AA range:36-85
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 18kD
GeneID: 6647
Human Swiss-Prot No: P00441
Cellular localization: Cytoplasm . Mitochondrion . Nucleus . Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria. .
Background: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008],
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