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SMIF rabbit pAb
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ES3467
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

Product name: SMIF rabbit pAb
Reactivity: Human;Mouse
Alternative Names: DCP1A; SMIF; mRNA-decapping enzyme 1A; Smad4-interacting transcriptional co-activator; Transcription factor SMIF
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human DCP1A. AA range:111-160
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 75kD
GeneID: 55802
Human Swiss-Prot No: Q9NPI6
Cellular localization: Cytoplasm, P-body . Nucleus . Co-localizes with NANOS3 in the processing bodies (By similarity). Predominantly cytoplasmic, in processing bodies (PB) (PubMed:16364915). Nuclear, after TGFB1 treatment. Translocation to the nucleus depends on interaction with SMAD4 (PubMed:11836524). .
Background: Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014],
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