SF3B14; CGI-110; HSPC175; HT006; Pre-mRNA branch site protein p14; SF3b 14 kDa subunit
Source:
Rabbit
Dilutions:
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:
The antiserum was produced against synthesized peptide derived from human SF3B14. AA range:76-125
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
14kD
GeneID:
51639
Human Swiss-Prot No:
Q9Y3B4
Cellular localization:
Nucleus .
Background:
This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site. [provided by RefSeq, Jul 2008],