The antiserum was produced against synthesized peptide derived from human ARHGEF1. AA range:162-211
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
105kD
GeneID:
9138
Human Swiss-Prot No:
Q92888
Cellular localization:
Cytoplasm . Membrane . Translocated to the membrane by activated GNA13 or LPA stimulation.
Background:
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008],