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Plakophilin 2 rabbit pAb
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ES3232
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: Plakophilin 2 rabbit pAb
反应性: Human;Rat
别名: PKP2; Plakophilin-2
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
免疫原: The antiserum was produced against synthesized peptide derived from human PKP2. AA range:632-681
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 97kD
基因ID: 5318
蛋白序列: Q99959
细胞定位: Nucleus . Cell junction, desmosome . Nuclear and associated with desmosomes.
研究背景: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008],
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