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MyD88 rabbit pAb
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ES2871
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

Product name: MyD88 rabbit pAb
Reactivity: Human;Mouse;Rat;Pig
Alternative Names: MYD88; Myeloid differentiation primary response protein MyD88
Source: Rabbit
Dilutions: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunocytochemistry: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MyD88. AA range:171-220
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 33kD
GeneID: 4615
Human Swiss-Prot No: Q99836
Cellular localization: Cytoplasm . Nucleus .
Background: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
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