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MLH1 rabbit pAb
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ES2797
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

Product name: MLH1 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human MLH1. AA range:441-490
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 85kD
GeneID: 4292
Human Swiss-Prot No: P40692
Cellular localization: Nucleus . Chromosome . Recruited to chromatin in a MCM9-dependent manner. .
Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009],
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