IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195
宿主:
Rabbit
稀释比:
WB 1:500-2000;IHC-p 1:50-300
免疫原:
The antiserum was produced against synthesized peptide derived from human IQGAP1. AA range:247-296
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
190kD
基因ID:
8826
蛋白序列:
P46940
细胞定位:
Cell membrane . Nucleus . Cytoplasm . Subcellular distribution is regulated by the cell cycle, nuclear levels increase at G1/S phase (PubMed:20883816). .
研究背景:
IQ motif containing GTPase activating protein 1(IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008],