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GRP1 rabbit pAb
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ES2482
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: GRP1 rabbit pAb
反应性: Human;Mouse;Rat;Monkey
别名: CYTH3; ARNO3; GRP1; PSCD3; Cytohesin-3; ARF nucleotide-binding site opener 3; Protein ARNO3; General receptor of phosphoinositides 1; Grp1; PH; SEC7 and coiled-coil domain-containing protein 3
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human GRP1. AA range:351-400
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 46kD
基因ID: 9265
蛋白序列: O43739
细胞定位: Cytoplasm, cytosol. Cell membrane ; Peripheral membrane protein . Cell junction, adherens junction . Cell junction, tight junction . Translocates from the cytosol to membranes enriched in phosphatidylinositol 3,4,5-trisphosphate. .
研究背景: This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq, Jul 2008],
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