GRB14 rabbit pAb-科鹿（武汉）生物科技有限责任公司

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GRB14 rabbit pAb

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ES2473

规格：	价格：
50µL	￥1280.00
100µL	￥1980.00

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Overview

Product name:	GRB14 rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	GRB14; Growth factor receptor-bound protein 14; GRB14 adapter protein
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human GRB14. AA range:81-130
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	61kD
GeneID:	2888
Human Swiss-Prot No:	Q14449
Cellular localization:	Cytoplasm . Endosome membrane ; Peripheral membrane protein . Upon insulin stimulation, translocates to the plasma membrane. .
Background:	The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],

Western Blot analysis of various cells using GRB14 Polyclonal Antibody
Western blot analysis of lysates from HUVEC, COLO, and MCF-7 cells, using GRB14 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human small intestinal carcinoma tissue. 1,primary Antibody was diluted at 1:200(4° overnight). 2, Sodium citrate pH 6.0 was used for antigen retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:2

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