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FAST rabbit pAb
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ES2328
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: FAST rabbit pAb
反应性: Human;Mouse;Rat
别名: FASTK; Fas-activated serine/threonine kinase; FAST kinase
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human FAST. AA range:361-410
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 61kD
基因ID: 10922
蛋白序列: Q14296
细胞定位: [Isoform 4]: Mitochondrion matrix . Colocalizes with mitochondrial RNA granules. .
研究背景: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008],
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