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DAN rabbit pAb
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ES2141
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: DAN rabbit pAb
反应性: Human;Rat;Mouse;
别名: NBL1; DAN; DAND1; Neuroblastoma suppressor of tumorigenicity 1; DAN domain family member 1; Protein N03; Zinc finger protein DAN
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human NBL1. AA range:131-180
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 19kD
基因ID: 4681
蛋白序列: P41271
细胞定位: Secreted.
研究背景: This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013],
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