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Cystatin 11 rabbit pAb
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ES2117
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Cystatin 11 rabbit pAb
反应性: Human;Rat;Mouse;
别名: CST11; CST8L; Cystatin-11
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human CST11. AA range:81-130
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 17kD
基因ID: 140880
蛋白序列: Q9H112
细胞定位: Secreted . Probably secreted into the epididymis lumen, where it localizes to the outer surface of sperm. Specifically localizes to the postacrosomal and tail regions of sperm. .
研究背景: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes an epididymal-specific protein shown to have antimicrobial activity against E. coli. Alternative splicing yields two variants encoding distinct isoforms. [provided by RefSeq, Sep 2014],
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