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STIP1/HOP Rabbit pAb
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ES20870
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: STIP1/HOP Rabbit pAb
反应性: Human; Mouse;Rat
别名: Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
宿主: Rabbit
稀释比: IHC-p1:50-200 ,WB 1:1000-2000
免疫原: Synthesized peptide derived from human STIP1/HOP AA range: 250-300
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 64kD
基因ID: 10963
蛋白序列: P31948
细胞定位: Cytoplasm . Nucleus . Dynein axonemal particle .
研究背景: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009],
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